This notion is further supported by our findings that positive HGMA2 staining in oral cancer cells is associated with many clinicopathological parameters (e.g., cervical metastasis), and the siRNA-mediated knockdown of HMGA2 attenuated in the migration and invasion capability of OSCC cells (Table 2 and Fig. 6). Here, HMGA2 is linked to lip and oral cavity carcinoma.