Statistical analysis of the immunohistochemical staining scores obtained from 199 paired samples revealed that the protein expression levels of HMGA2 and MIF were significantly higher in tumor cells compared to the non-tumor epithelia (60.9 ± 46.8 vs. 0, P < 0.001 and 223.3 ± 42.8 vs. 55.9 ± 50.6, P < 0.001, respectively; Fig. 4C). Here, HMGA2 is linked to neoplasm.