ARID4B and gastric cancer: In order to investigate the feasibility of applying RNA nanoparticles as theranostic agents for gastric cancer diagnosis and therapy, we designed the pRNA-3WJ nanoparticle consisting of three fragments, a3WJ, b3WJ and c3WJ, and functionalized with folate, as targeting ligand; Alexa647, as imaging module; and BRCAA1 siRNA (or scrambled control), as therapeutic module, respectively.