Newborn and very young infants with sickle cell anaemia (SCA) still produce significant amounts of foetal haemoglobin (HbF), the Hb that is made during intrauterine life, although this HbF production will begin to decline after the first few months due to the Hb-switching process (Quinn, 2013). The gene discussed is GSTM1; the disease is sickle cell disease.