Statistically significant protein-coding mutations identified included NRAS, KRAS, FAM46C, DIS3, TP53, CCND1, PNRC1, ALOX12B, HLA-A, and MAGED1. In addition, one patient had a BRAF kinase mutation (G469A) prompting genotyping of an additional 161 MM samples for the 12 most common BRAF mutations. The gene discussed is TP53; the disease is Miyoshi myopathy.