These apparent discrepancies may result from marked differences in the authors' use of (i) antibodies specific for PfEMP1 variants expressed by parasite lines ITvar9 and TM284var1 (vs. FVO, A4tres, and FCR3CSA); (ii) four laboratory-adapted parasite lines (vs. multiple naturally-circulating parasite isolates from Malian children with malaria); and (iii) purified CD36 and ICAM1 proteins as binding substrates (vs. CD36-expressing MVECs and monocytes). The gene discussed is CD36; the disease is malaria.