Fever (>7 days), hepatosplenomegaly with liver dysfunction, pancytopenia, sCD25 (>2400μg/mL), ferritin (>500 μg/L), triglycerides (>3 mmol/L), hypofibrinogenemia (<150 mg/dL), serum cytokine levels of both IFNg (>75 pg/ml) + IL-10 (>60 pg/ml) ↑. This evidence concerns the gene IFNG and Decreased liver function.