We have considered these inclusion criteria: (1) pain clearly located in the thyroidal region, severe, spontaneous, and exacerbated by palpation, (2) increased erythrocyte sedimentation rate above 40 mm/h and/or elevated C reactive protein, (3) clinical and ultrasonographic exclusion of causes of thyroid pain other than thyroiditis, as those reported in the Introduction, and (4) thyroid ultrasonography consistent with thyroiditis, according to well established criteria [8, 9]. The gene discussed is CRP; the disease is thyroiditis.