Only two forms inherited as autosomal dominant and recessive traits respectively are caused by mutations in genes coding for proteins directly involved in iron metabolism: neuroferritinopathy due to ferritin light chain gene (FTL) (MIM#606159) mutation (Chinnery et al., 2007) and aceruloplasminemia linked to mutations in the ceruloplasmin gene (CP) (MIM#117700) (McNeill et al., 2008). This evidence concerns the gene CP and neuroferritinopathy.