BARP KO mice showed increased working memory ability, PPI, and social interaction, and decreased locomotor activity and perseveration, which are opposite to those generally considered as core features of schizophrenia (Braff and Geyer, 1990; Crider, 1997; Elvevag and Goldberg, 2000; Powell and Miyakawa, 2006), though many of the behavioral results suggesting these phenotypes achieved only nominal statistical significance and require further replication. The gene discussed is CBARP; the disease is schizophrenia.