SLC6A3 and schizophrenia: In addition, greatly reduced vertical activity and stereotypic behavior counts in the open-field test in the mice are also in contrast to the behavioral phenotypes of some mouse models of schizophrenia and its related disorders, such as dopamine transporter KO mice, dominant-negative Disrupted-in-Schizophrenia-1 transgenic mice, Schnurri-2 KO mice, forebrain-specific calcineurin KO mice, and α-CaMKII heterozygous KO mice (Giros et al., 1996; Miyakawa et al., 2003; Hikida et al., 2007; Yamasaki et al., 2008; Takao et al., 2013).