It has been reported that IL-17A has proangiogenic effects but in a HIF-1α-independent pathway; however, at the same time, IL-17A can stimulate the expression of proangiogenic factors in fibroblast and keratinocytes, including VEGF, feeding back the angiogenesis in psoriasis (Figure 1, p) [99–101]. Here, HIF1A is linked to psoriasis.