Antibodies against arthritis-related protein (Arp), decorin-binding protein A (DbpA), outer-surface protein C (OspC), and the outer surface protein BmpA of cN40 Bb are not only highly immunogenic, they also passively protect from infection or are involved with resolution of arthritis and carditis, or both [24–27]. The gene discussed is YBX3; the disease is inflammation of heart layer.