MBL2 and diabetes mellitus: With an AUC of 0.86 (95% CI, 0.80–0.92), MBL showed a significantly greater discriminatory ability to diagnose VTDR as compared with Hs-CRP (AUC, 0.61; 95% CI, 0.53–0.70; P<0.0001), HbA1c (AUC, 0.69; 95% CI, 0.60–0.78; P<0.0001) and age (AUC, 0.59; 95% CI, 0.53–0.64; P<0.001), while was in the range of diabetes duration (AUC, 0.85; 95% CI, 0.77–0.92; P = 0.126; Fig 4B).