INS and neoplasm: Similarly, the serum insulin levels were also considerably lower in the 2-DG fed mice in comparison to the control in tumor bearing condition (0.39 ± 0.02 and 0.36 ± 0.03 ng/ml for 0.2% (p < 0.05) and 0.4% (p < 0.01) 2-DG groups respectively versus 0.5 ± 0.02 ng/ml for the control group; Fig 8B).