At a concentration of 100 μmol/l of 5-FU relative cell viability of TLR7+ and TLR8+ PANC1 tumor cells was less reduced when compared with empty vector PANC1 tumor cells (Fig. 8B; 62 and 73% vs. 58% for empty vector cells; P<0.05 and P<0.0001). The gene discussed is TLR8; the disease is neoplasm.