We found that 6 out of 8 (75%) Tg(fabp10a:pt-β-cat) livers with HCC contained foci with moderate or strong nuclear phospho-c-Jun staining, while 0 out of 7 control livers without activated β-catenin showed such staining (Fig 5C; p<0.01, Fisher’s exact test). Here, PPIB is linked to hepatocellular carcinoma.