IFI16 and infection: When lysates from HMVEC-d cells infected with KSHV or UV-KSHV for 24 h were IP-ed with anti-acetylated lysine antibody and western blotted for IFI16, similar to live-KSHV infected cells, acetylation of IFI16 increased in a time dependent manner by infection with UV-KSHV (Fig 2C, lanes 1–7).