In a study using a total of 82 tumor cell lines, Ying et al (26) showed that the expression of PTPL1 was frequently downregulated or silenced in NHL (94%, 15/16), Hodgkin lymphoma (50%, 3/6), breast (30%, 3/10), gastric (60%, 6/10) and hepatocellular (67%, 8/12) carcinoma cell lines. The gene discussed is PTPN13; the disease is carcinoma.