In addition, the methylation pattern of several genes were identified in lymphoma, such as SHP1, CD44, DAPK, GSTP1, MGMT, P14, P15, P16, P33, RB1, hMLH1, CDH1, APC, RASSFA1, TIMP3, VHL and BLU (17–20). Here, CD44 is linked to lymphoma.