In addition, the methylation pattern of several genes were identified in lymphoma, such as SHP1, CD44, DAPK, GSTP1, MGMT, P14, P15, P16, P33, RB1, hMLH1, CDH1, APC, RASSFA1, TIMP3, VHL and BLU (17–20). This evidence concerns the gene TIMP3 and lymphoma.