Among these genes, we observed metastasis associated genes e.g., tumor biomarker CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5), metabolic genes e.g. INSIG1 (insulin induced gene 1) LIPG (endothelial lipase) and messenger molecule genes DAPP1(dual adaptor of phosphotyrosine and 3-phosphoinositides), CREB3L2 (cAMP responsive element binding protein 3-like 2) (Table 2). The gene discussed is CREB3L2; the disease is neoplasm.