Suppressed fasting blood levels of glycated hemoglobin A1c, glucose, insulin, total triglycerides, free fatty acids, total cholesterol, low density lipoprotein-cholesterol, high-sensitivity C-reactive protein and nitric oxide, but elevated levels of high density lipoprotein-cholesterol, insulin sensitivity index bradykinin, prostacyclin, and adiponectin were noted in Chinese patients with type 2 diabetes mellitus following daily treatment with 13 g marine collagen peptides from fish hydrolysate for 1.5 and 3 months [117]. Here, INS is linked to diabetes mellitus.