We also emphasize the 12 common genes (CEP55, ESR1, FOXA1, FOXC1, KRT17, MAPT, MELK, MMP11, NAT1, SFRP1, UBE2C, and UBE2T) due to their important role for breast cancer disease and intrinsic subtyping. This evidence concerns the gene SFRP1 and breast cancer.