SULF1 and Infertility: Therefore, with respect to the role of growth factors and morphogenesis in the evolution stages of fetus and SULF1 role in angiogenesis and implantation, in this research we have studied rs6990375 polymorphism of SULF1 gene as a clinical polymorphism in infertile women with the background of at least once failure in IVF (16, 17).