Notch1 5ʹ deletions detected by CGH (S1 Fig) were more frequently associated with tumours that did not harbour trisomy 15 (7/10, 70%) over those with trisomy 15 (5/21, 24%, P = 0.021, Fisher’s Exact) suggesting a redundancy between the Notch1 and Myc pathways. This evidence concerns the gene NOTCH1 and neoplasm.