Recent studies by Murakami et al. [150] have suggested that in the human pancreatic cancer cell line, MIAPaCa-2, phosphorylation of NDRG1 at Ser330 and Thr346 is essential for its tumor-suppressive action on CXC chemokine expression and the nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This evidence concerns the gene NDRG1 and familial pancreatic carcinoma.