AFP and metastatic malignant neoplasm in the lymph nodes: In addition to a high FAM83D expression level, a value of AFP ≥100 ng/ml, a tumor ≥5 cm, the presence of multiple tumors, TNM stage III-IV, the presence of PVTT, the presence of distant metastasis or lymph node metastasis, AST ≥40 U/l and NLR ≥2.31 were associated with a shorter DFS and OS (Table 2).