Future studies will concentrate on the relationship between 4,4′-Br2DIM, CaMKII and mitochondrial dysfunction, the effectiveness of this potent anti-cancer compound in animal models of prostate cancer, and the potential for targeting the ER stress and autophagy pathways in order to increase the effectiveness of the ring-DIMs and DIM as anti-neoplastic agents. This evidence concerns the gene CAMK2G and prostate cancer.