In the current meta-analysis, we included all the studies investigating the association between PSCA polymorphisms and cancer risk, i.e., a total of 32 studies with 30028 cases and 38765 controls for the PSCA rs2294008 C>T polymorphism, and 14 studies with 8190 cases and 7176 controls for the PSCA rs2976392 G>A polymorphism. Here, PSCA is linked to cancer.