Overall, there were 32 studies investigating the association between PSCA rs2294008 C>T polymorphism and cancer susceptibility, consisting of 30028 cases and 38765 controls [8, 9, 14-35, 39-43], and 14 studies performed on the relation between PSCA rs2976392 G>A polymorphism and overall cancer susceptibility, with 8190 cases and 7176 controls [8, 14-17, 19, 24, 29, 36-39, 43]. The gene discussed is PSCA; the disease is cancer.