In PCOS and non-PCOS women, levels of TNF-α [26, 27], IL-6, and CRP [27] correlate directly with BMI, but overweight and obese PCOS women in some studies have presented with significantly higher levels of these inflammatory markers than their BMI-matched non-PCOS counterparts [10, 27]. This evidence concerns the gene CRP and polycystic ovary syndrome.