MIF and Hepatic steatosis: In line with these results, Heinrichs et al. (63) observed that hepatic steatosis was reduced in absence of MIF in both HFD-fed (60 kcal% fat, 16 weeks) and methionine and choline-deficient (MCD) diet-fed (8 weeks) Mif−/− mice (sex and age not specified, C57BL/6 background).