The observed reduction in hepatic steatosis (analyzed by histological Oil Red O staining and biochemical measurement of hepatic triglycerides) was accompanied by increased lipogenic gene expression (i.e., transcription factors Lxra and Srebp-1, and enzymes Acc, Fas, Dgat1, Dgat2), which was also observed in the MCD diet-fed mice. The gene discussed is DGAT1; the disease is Hepatic steatosis.