NFKB1 and early-onset autosomal dominant Alzheimer disease: Not surprisingly, NFκB has been implicated in the pathogenesis of Parkinson’s disease (PD), Huntingdon’s disease (HD), Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), MS and stroke (Kaltschmidt et al., 1999; Dasgupta et al., 2004; van Loo et al., 2006; Ghosh et al., 2007; Sarnico et al., 2009; Marcora and Kennedy, 2010; Baiguera et al., 2012; Hsiao et al., 2013).