AKT1 and hepatocellular carcinoma: However, we did not believe that the high p-AKT expression levels were due to the high total AKT expression levels because the ratios of AKT/GAPDH were up-regulated 2- to 3-fold, while the ratios of p-AKT/AKT were up-regulated more obviously (3- to 5-fold) in the HCC tissues compared to the normal liver tissues (Supplementary Figure 6A-6B).