Moreover, MMP3 rs35068180 polymorphism might be associated with a lower risk of aggressive periodontitis (AgP) in Asians (allelic genetic model: OR = 0.66, 95% CI: 0.48–0.91, Pheterogeneity = 0.945), and CP in Caucasians and Brazilians. The gene discussed is MMP3; the disease is periodontitis, aggressive.