LIN28B and cancer: A recent study revealed that LIN28A/LIN28B mRNA contains an AU-rich element (ARE) within its 3′UTR, and the tumor suppressor tristetraprolin (TTP), an ARE binding protein, enhances the degradation of LIN28A/LIN28B mRNA; however, TTP is often repressed in human cancers, which may also contribute to the elevation of LIN28A/LIN28B in certain cancer types [36].