Seven genes were down-regulated in the biopsies of celiac disease patients, among them NTS down-regulated 3.6 fold and the INSR, APPL2, ADCY9, GLS, HSPB1 and KIF13A 1.5-2.2 fold in the patient group (p < 0.001). The gene discussed is HSPB1; the disease is celiac disease.