However, a combination treatment with tectochrysin and TRAIL enhanced TRAIL induced cell growth inhibition up to 49.6 % in HT-29 TRAIL-resistant colon cancer cells, 40.7 % in A549 TRAIL-resistant lung cancer cells and 46.8 % in MCF-7 TRAIL-resistant breast cancer cells (Fig. 5a). The gene discussed is TNFSF10; the disease is malignant colon neoplasm.