CXCL10 and cardiomyopathy: Our ongoing studies are, indeed, toward this direction, and aimed to evaluate PDE5i activity in vivo on circulating level of several Th1-related chemokines, first of all CXCL10, measured in early stages of cardiomyopathies and in vitro on different human cell types, such as endothelial, cardiac and immune cells, to clarify the cellular targets.