CD4 and infection: Our analyses of 301 samples from the studied subjects who received a baseline detection of viral load showed that median viral load was higher in CRF01_AE infection than in CRF07_BC infection (p<0.01), indirectly supporting the finding of an increased rate of CD4+T cell count decline in CRF01_AE-infected patients compared with non-CRF01_AE patients [44].