DAVID analysis of DE genes identified in the BVDV challenged vs control animals, revealed pathways for ECM-receptor interaction, focal adhesion, lysosome, complement and coagulation cascades, cell adhesion molecules, leukocyte transendothelial migration, cancer associated pathways, VEGF signaling, toll-like receptor signaling, TGF-beta signaling, MAPK signaling, and T cell receptor signaling (S4 Table). This evidence concerns the gene VEGFA and cancer.