FGF21 and metabolic dysfunction-associated steatotic liver disease: After analyzing the serum biomarker levels in training group and controls, we found that CK-18-M30, IL-1Ra, FGF-21 and PEDF were significantly higher in NAFLD training group (median 18.30 ng/L, 104.80 ng/L, 39.30 ng/L, and 33.50 μg/L respectively) than controls (median 14.10 ng/L, 47.10 ng/L, 16.60 ng/L and 18.70 μg/L respectively).