Of these, SNP rs7429015 is located in the intron of gene KCNMB2 that encodes the potassium large conductance calcium-activated channel subunit β2; SNP rs2436106 is located within gene KCNQ3 which is part of a family potassium voltage-gated channel protein associated with NIHL [32], [33]; and SNP rs4374858 is located within 20 kb of gene GPR6, which encodes a G protein-coupled receptor. This evidence concerns the gene GPR6 and noise induced hearing loss.