LEP and head and neck squamous cell carcinoma: The present study identified changes in levels of the pro-inflammatory cytokines, IL-6 and IL-17, and the pro- and anti-inflammatory adipokines, leptin and adiponectin, in patients with premalignant oral lesions or in patients that have developed HNSCC that were either untreated or treated with 1,25(OH)2D3 to modulate immune reactivity.