If compared with cardiometabolic risk factors-free subjects those presenting 1 or 2 risk factors displayed significantly lower eGFR and adiponectin levels, higher uric acid and hsCRP concentrations, but similar levels of leptin, resistin, CML/Alb, AGE-Fl/Alb and sRAGE. Here, LEP is linked to chronic myelogenous leukemia, BCR-ABL1 positive.