AVP and heart failure: The prognostic role of copeptin has been reported in various types of acute illness, including hemorrhagic/septic shock, lower respiratory tract infection, heart failure, and acute myocardial infarction5, 6, 8, 21, 22, 23; a higher copeptin level has been associated with all of these conditions and also predicts outcomes following heart failure and acute myocardial infarction.