Indeed, reactivation of IGF2 expression on the maternal allele has been previously reported in a number of human tumors and tumor cell lines (Li et al., 1995; Singer et al., 1995; Takeda et al., 1996; Zhang et al., 1997; Cui et al., 1998; Hofmann et al., 2002). The gene discussed is IGF2; the disease is neoplasm.