All sera tested positive for total-anti-HBc: their levels were significantly lower in HBsAg-carriers without HBV-induced liver disease (median 3.26, range 2.26–4.49Log10IU/ml) as compared to untreated CHB-patients (4.68,2.76–5.54Log10IU/ml) (p<0.0001), Fig 1. Here, KRT88P is linked to liver disorder.