Three months postpartum, neither betatrophin nor irisin levels differed significantly between the women with prior GDM and NGT (2.02 [1.16–3.14] ng/ml vs 2.19 [1.67–3.06] ng/ml and 1109 [841–1495] ng/ml vs 1137 [822–1372] ng/ml, respectively, Figs 1 and 2). Here, FNDC5 is linked to gestational diabetes.