We described the serum kinetics of IP-10, IFNy, IL-6, MIG, TNFα, and MCP-1 before and during the first two weeks of treatment in patients with presumptive TB to explore whether cytokine responses have the potential to confirm a clinical diagnosis in patients without bacteriological confirmation and be used as early surrogate markers of treatment response to identify drug-resistant TB. Here, IL6 is linked to tuberculosis.