Multiple cancer‐associated single‐nucleotide polymorphisms (SNPs) have been mapped to conserved sequences within a 500‐kilobase region upstream of the MYC oncogene on human chromosome 8q24, and mice lacking a Myc enhancer (Myc‐335) that includes human SNP rs6983267 are resistant to intestinal tumours induced by the ApcMin mutation 91. Here, MYC is linked to cancer.