NFKB1 and endothelial dysfunction: However our data point out to a global interference by DHA with the expression of NF-κB target genes, as well as with modulators of such activation, confirming and expanding the anti-inflammatory and anti-atherogenic activities highlighted in vivo [21, 23, 25, 26] and providing new molecular explanations to evaluate the role of fish oil-derived n-3 PUFAs in the context of diseases featuring endothelial dysfunction.