Analysis of 32 serum cytokine/chemokine markers revealed an increase in 11 cytokines with cancer compared to PBS-injected mice: interferon gamma (IFN-γ), interleukin- (IL-) 2, IL-4, IL-5, IL-12 (p40), IL-1β, IL-1α, interferon gamma-induced protein-10 (IP-10), macrophage colony-stimulating factor (M-CSF), macrophage inflammatory protein-2-alpha (MIP-2), and monokine-induced by gamma interferon (MIG). This evidence concerns the gene CXCL2 and cancer.