Information for PatientsAll three conditions are chronic, and cannot be completely cured. We expect anti-VEGF injections to improve vision in exudative AMD and diabetic maculopathy in most – but not all – patients. In glaucoma and proliferative DR, treatment will only prevent the condition getting worse. In order to manage these chronic and incurable disorders effectively, patients must attend the clinic regularly for the rest of their lives. The gene discussed is VEGFA; the disease is age-related macular degeneration.